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一、国内学者使用康成Exiqon microRNA芯片技术服务发表的SCI成果—平均影响因子5.5分以上
→  Altered microRNAs expression profiling in experimental silicosis rats. J TOXICOL SCI. 2012.
→  The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel-1C. Hypertensionaha. 2012.
→  miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1. Cancer science. 2012.
→  MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN. The Journal of Immunology. 2012
→  Glucocorticoids inhibit lipopolysaccharide-mediated inflammatory response by downregulating microRNA-155: a novel anti-inflammation mechanism. Free Radical Biology & Medicine. 2012.
→  Suppression of Type I Collagen Expression by miR-29b via PI3K, Akt, and Sp1 Pathway in Human Tenon’s Fibroblasts. Glaucoma. 2012.
→  Overexpression of miR-125b, a novel regulator of innate immunity, in eosinophilic chronic rhinosinusitis with nasal polyps. American Thoracic Society.Am. J. Respir. Crit. 2011.
→  Dysregulated expression of miR-146a contributes to agerelated dysfunction of macrophages. Anatomical Society of Great Britain and Ireland. 2011.
→  MicroRNA-135a contributes to the development of portal vein tumor thrombus by promoting metastasis in hepatocellular carcinoma. Journal of Hepatology. 2011.
→  Signature microRNA Expression Profile of Essential Hypertension and Its Novel Link to Human Cytomegalovirus Infection. Circulation. 2011.
→  Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. J Pathol. 2011.
→  MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. Carcinogenesis. 2011.
→  Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis. Molecular Immunology. 2011.
→  A microRNA profile comparison between thoracic aortic dissection and normal thoracic aorta indicates the potential role of microRNAs in contributing to thoracic aortic dissection pathogenesis. JOURNAL OF VAS CULAR SURGERY. 2011.
→  Upregulation of Mir-21 Mediates Resistance to Trastuzumab Therapy for Breast Cancer. Journal of Biological Chemistry. 2011.
→  MicroRNA Expression Analysis: Clinical Advantage of Propranolol Reveals Key MicroRNAs in Myocardial Infarction. PLoS ONE. 2011.
→  MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145. World J Gastroenterol. 2011.
→  Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues. Int J Oral Sci. 2011.
→  TLR9 agonist enhances lung cancer invasiveness by alternating miRNA expression profile.  Scientific Research and Essays. 2011.
→  Identification of microRNA-target interaction in APRIL-knockdown colorectal cancer cells. Cancer Gene Therapy. 2011.
→  MicroRNA-224 Is Involved in Transforming Growth Factor-β-Mediated Mouse Granulosa Cell Proliferation and Granulosa Cell Function by Targeting Smad4. J., Mol. Endocrinol. 2010.
→  MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor. Plos Genetics. 2010.
→  A Novel Function of MicroRNA Let-7d in Regulation of Galectin-3 Expression in Attention Deficit Hyperactivity Disorder Rat Brain. Brain Pathol. 2010.
→  miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27Kip1-and MEK/ERK-mediated cell cycle regulation. Biological Chemistry. 2010.
→  Up-regulation of microRNA in bladder tumor tissue is not common. Int Urol Nephrol. 2010.
→  MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression. J Biol Chem. 2010.
→  Regulation of NADPH Oxidase Activity Is Associated with miRNA-25-Mediated NOX4 Expression in Experimental Diabetic Nephropathy. American Journal of Nephrology. 2010.
→  Differential expression of microRNAs in porcine placentas on Days 30 and 90 of gestation. Reproduction, Fertility and Development. 2010.
→  MicroRNA profiling in mid- and late-gestational fetal skin: implication for scarless wound healing. Tohoku J Exp Med. 2010.
→  differential expression profiles of microRNAs in NIH3T3 Cells in Response to UVB Irradiation. Photochemistry and Photobiology. 2009.
→  Altered microRNA expression in patients with non-obstructive azoospermia. Reprod. Biol. Endocrinol. 2009.
→  Regulation of Hepatic MicroRNA Expression in Response to Ischemic Preconditioning following Ischemia=Reperfusion Injury in Mice. OMICS A Journal of Integrative Biology. 2009.
→  MicroRNA: Novel Regulators Involved in the Remodeling and Reverse Remodeling of the Heart. Cardiology. 2009.
→  Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis. EMBO J. 2009.
→  miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis. J Hepatol. 2009.
→  Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways. FEBS J. 2009.
→  Embryonic stem cells derived from somatic cloned and fertilized blastocysts are post-transcriptionally indistinguishable: A MicroRNA and protein profile comparison.  Proteomics. 2009.
→  Altered gene expression and miRNA expression associated with cancerous IEC-6 cell transformed by MNNG. J Exp Clin Canc Res. 2009.
→  Differential microRNA expression in childhood B-CELL precursor acute lymphoblastic leukemia. Pediatric Hematology-Oncology. 2009.
→  Differential expression of miRNA patterns in renal cell carcinoma and nontumorous tissues. J CANCER RES CLIN. 2009.
→  Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. CLIN EXP PHARMACOL P. 2009.
→  MicroRNA expression and regulation in mouse uterus during embryo implantation. J Biol Chem. 2008.
→  Microarray analysis of microRNA expression in hepatocellular carcinoma and non-tumorous tissues without viral hepatitis. J Gastroen Hepatol. 2008.
→  Identification of Differentially Expressed MicroRNAs During the Development of Chinese Murine Mammary Gland. Journal of Genetics and Genomics. 2007.

二、国内学者使用康成Exiqon microRNA PCR芯片技术服务发表的SCI成果
→  High dose glargine alters the expression profiles of microRNAs in pancreatic cancer cells.World Journal of Gastroenterology.2012.
→  Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells. diabetes research and clinical practice. 2012.

三、国内学者使用康成Arraystar LncRNA芯片服务发表的SCI成果
→  Genome-wide analysis of long noncoding RNA expression in peripheral blood mononuclear cells of uremia patients. J Nephrol. 2012.
→  LncRNA profile of glioblastoma reveals the potential role of lncRNAs in contributing to glioblastoma pathogenesis. International Journal of Oncology. 2012.
→  Transcriptome analysis of long noncoding RNAs of the nucleus accumbens in cocaine-conditioned mice. Journal of Neurochemistry. 2012.
→  HBx-related lncRNA Dreh inhibits  hepatocellular  carcinoma metastasis  by  targeting the intermediate filament protein vimentin. Hepatology. 2012.
→  Epigenetic Activation of the MiR-200 Family Contributes to H19 mediated Metastasis Suppression in Hepatocellular Carcinoma. Carcinogenesis. 2012.
→  lncRNA expression signatures in response to enterovirus 71 infection. Biochem. Biophys. Res. Commun. 2012.
→  Long non-coding RNA-MVIH promotes angiogenesis and serves as a predictor  for HCC patients’ poor recurrence-free survival after hepatectomy. Hepatology. 2012.
→  LncRNAs Expression Signatures of Renal Clear Cell Carcinoma Revealed by Microarray. PloS one. 2012.
→  LncRNA profile of glioblastoma reveals the potential role of lncRNAs in contributing to glioblastoma pathogenesis.  International journal of oncology. 2012. 
→  Long non-coding RNA high expressed in hepatocellular carcinoma (lncRNA-HEIH) facilitates tumor growth through enhancer of zeste homolog 2. Hepatology. 2011.

→  Identification and Characterization of Novel Immunomodulatory Bursal-derived Pentapeptide-II (BPP-II). J Biol Chem. 2012.
→  Screening and functional analysis of differentially expressed genes in EBV-transformed lymphoblasts. Virol J. 2012.
→  Gene expression profiling of hybridoma cells after bursal-derived bioactive factor BP5 treatment. Amino Acids. 2012.
→  Efficacy analysis of combining three comparative-omics profilings to screen candidate biological macromolecules. Molecular Biology Reports. 2012.
→  Gene Expression Analyses of Subchondral Bone in Early Experimental Osteoarthritis by Microarray. plos one. 2012.
→  Diabetes causes multiple genetic alterations and downregulates expression of DNA repair genes in the prostate. Laboratory Investigation. 2011.
→  LM23 is a novel member of the Speedy/Ringo family at the crossroads of life and death of spermatogenic cell. Asian Journal of Andrology. 2011.
→  Global transcriptional profiles of Mycobacterium tuberculosis treated with plumbagin. World Journal of Microbiology and Biotechnology. 2011.
→  Microarray Analysis of the Chelerythrine-Induced Transcriptome of Mycobacterium tuberculosis. Current microbiology. 2011.
→  Gene expression profiling: identification of genes with altered expression in Ayu17-449 knockout mice. Genetics and Molecular Research. 2011.
→  Calcium Prevents Tumorigenesis in a Mouse Model of Colorectal cancer. PLOS ONE. 2011.
→  Gene expression signature of lymphocyte in acute lymphoblastic leukemia patients immediately after total body irradiation. LEUK RES. 2011.
→  Apigenin inhibits hepatoma cell growth through alteration of gene expression patterns. Phytomedicine. 2011.
→  The existence of multipotent stem cells with epithelial–mesenchymal transition features in the human liver bud. Int J Biochem Cell Biol. 2010.
→  Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma. Oncogene. 2010.

→  L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro. PLoS One. 2012.
→  Gene Expression Profiling of Rat Testis Development During the Early Post‐Natal Stages. Reproduction in Domestic Animals. 2011.
→  Small interfering RNAs screened from random siRNA library direct neuronal differentiation. Biotechnology letters. 2011.
→  MicroRNA-135a Contributes to the Development of Portal Vein Tumor Thrombus by Promoting Metastasis in Hepatocellular Carcinoma. Journal of Hepatology. 2011.
→  HDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs. Cell Res. 2011.
→  Random small interfering RNA library screen identifies siRNAs that induce human erythroleukemia cell differentiation. Leuk Lymphoma. 2011.
→  From the Cover: Feature Article: Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. Proc Natl Acad Sci U S A. 2011.

六、国内学者使用康成SABiosciences PCR芯片技术服务发表的SCI成果
→ Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce ithelialemesenchymal transition. Gut.2012.
→ Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma. Journal of Hepatology. 2011.
→ ShRNA-Targeted Centromere Protein A Inhibits Hepatocellular Carcinoma Growth. Plos One. 2011.
→  Escin attenuates cognitive deficits and hippocampal injury after transient global cerebral ischemia in mice via regulating certain inflammatory genes. Neurochem Int. 2010.
→  The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor. Carcinogenesis. 2010.
→  Gene expression profile towards the prediction of patient survival of gastric cancer. Biomed Pharmacother. 2010.
→  Effect of burn injury on apoptosis and expression of apoptosis-related genes/proteins in skeletal muscles of rats. Apoptosis. 2009.
→  Effects of chronic mild stress on the development of atherosclerosis and expression of toll-like receptor 4 signaling pathway in adolescent apolipoprotein E knockout mice. J Biomed Biotechnol. 2009.
→  Identification of liver metastasis-related genes in a novel human pancreatic carcinoma cell model by microarray analysis. Cancer Lett. 2009.

→  cAMP response element-binding protein promotes gliomagenesis by modulating the expression of oncogenic microRNA-23a. PNAS. 2012.
→  CRL4B Catalyzes H2AK119 Monoubiquitination and Coordinates with PRC2 to Promote Tumorigenesis. Cancer Cell. 2012.
→  125I seed irradiation induces up-regulation of the genes associated with apoptosis and cell cycle arrest and inhibits growth of gastric cancer xenografts. Journal of Experimental & Clinical Cancer Research. 2012.
→  Genome-wide analysis of HMGA2 transcription factor binding sites by ChIP on chip in gastric carcinoma cells. Mol Cell Biochem. 2012.
→  Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma. PLoS One. 2011.
→  MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human gl, ioma, Molecular Cancer. 2011.
→  Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells. Journal of Experimental & Clinical Cancer Research. 2011.
→  Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet. 2011.
→  Genome-wide DNA methylation patterns in IVF-conceived mice and their progeny: A putative model for ART-conceived humans. Reprod Toxicol. 2011.
→  Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas. Neuro Oncol. 2010.
→  Genome-wide analysis of histone H3 lysine 4 trimethylation in peripheral blood mononuclear cells of minimal change nephrotic syndrome patients. Am J Nephrol. 2009.
→  Genome-wide analysis of histone H3 lysine 27 trimethylation by ChIP-chip in gastric cancer patients. J Gastroenterol. 2009.
→  The N-terminus of histone H3 is required for de novo DNA methylation in chromatin. Proc Natl Acad Sci U S A. 2009.

→  Nitric Oxide-Driven Hypoxia Initiates Synovial Angiogenesis, Hyperplasia and Inflammatory Lesions in Mice. PLoS One. 2012.
→  Lack of apoE causes alteration of cytokines expression in young mice liver. Mol Biol Rep. 2010.
→  Increased inflammatory response both in brain and in periphery in presenilin 1 and presenilin 2 conditional double knock-out mice. J Alzheimers Dis. 2009.
→  Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery. Cytotherapy. 2009.
→  Evaluation of immune inhibitory cytokine profiles in epithelial ovarian carcinoma. J Obstet Gynaecol Res. 2009.
→  Induction of inflammatory cytokine release from huma, , , n umbilical vein endothelial cells by agonists of proteinase-activated receptor-2. Clin Exp Pharmacol Physiol. 2008.
→  Induction of lytic cycle replication of Kaposi's sarcoma-associated herpesvirus by herpes simplex virus type 1: involvement of IL-10 and IL-4. Cell Microbiol. 2008.
→  Dysfunction of splenic macrophages in cirrhotic patients with hypersplenism and HBV infecti, on. Am J Med Sci. 2008.
→  LPS-induced down-regulation of signal regulatory protein alpha contributes to innate immune activation in macrophages. J Exp Med. 2007.

→  Comparison between two kinds of cigarette smoke condensates (CSCs) of the cytogenotoxicity and protein expression in a human B-cell lymphoblastoid cell line using CCK-8 assay, comet assay and protein microarray. Mutat Res. 2010.
→  IPO-38 is identified as a novel serum biomarker of gastric cancer based on clinical proteomics technology. J Proteome Res. 2008.

→  Stage-Associated Dynamic Activity Profile of Transcription Factors in Nasopharyngeal Carcinoma Progression Based on Protein/DNA Array Analysis. OMICS A Journal of Integrative Biology.2011.

十一、国内学者使用康成Agilent aCGH芯片技术服务发表的SCI成果
→  The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor. Carcinogenesis, 2010.  primary amenorrhea and hyperandrogenism. Int J Gynaecol Obstet. 2010.

十二、国内学者使用康成Nimblegen aCGH芯片技术服务发表的SCI成果
→  Array-CGH detection of UGT2B28 gene deletion in a girl with primary amenorrhea and hyperandrogenism. Int J Gynaecol Obstet. 2010.



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From Transcriptomics to Proteomics 康成生物2017技术热点巡回讲座火热开启!
康成独家推出Small RNA测序系列技术服务
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暑期特惠 夏不为利:Exiqon microRNA芯片买5赠1!
最新推出:Arraystar Mouse LncRNA Expression Microarray V3.0
Cell最新发表:应用Arraystar LncRNA芯片研究乳腺癌的文章
分享LncRNA文章成功故事 赠送友情好礼
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巡回讲座:Lead,Never Follow——开拓ncRNA新视野,解读表观遗传新概念
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经典与创新2015康成秋季巡回讲座:Innovation, Never Stops!
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秋实硕果:miRStar Human Cancer focused microRNA PCR Array首推特惠3988元
国外学者使用Exiqon microRNA Microarray发表的SCI文章列表
郑重声明:康成继续提供Roche NimbleGen平台芯片技术服务
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