——The MeDIP-chip assay in the research was supplied by Kangchen Biotech Inc.
Article publishe online 13 March 2011
Title: Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.
Author info: Zhu Chen and Sai-Juan Chen are both Academicians of the Chinese Academy of Sciences
Content of the MeDIP-chip experiment in the article:
1. Supplementary Figure 8 ( page 8 ): Found 3237 differentially methylated genes between DNMT3A mutated and wildtype groups. Pathway analysis showed significantly enriched pathways of genes of hypermethylation or hypomethylation.
2. Supplementary Table8,9 (page 18~101): Detailed information of the 3237 differentially methylated genes discovered by MeDIP-chip assay.
News