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→ The MicroRNA-328 Regulates Hypoxic Pulmonary Hypertension by Targeting at Insulin Growth Factor 1 Receptor and L-Type Calcium Channel- 1C., Lei Guo.2012. hypertensionaha. (New)

→miR-30c-1* promotes natural killer cell cytotoxicity against human hepatoma cells by targeting the transcription factor HMBOX1., Jiuyu Gong, et al. 2012. Cancer science. (New)

→MicroRNA-494 Is Required for the Accumulation and Functions of Tumor-Expanded Myeloid-Derived Suppressor Cells via Targeting of PTEN.,Yang Liu,et al. 2012 The Journal of Immunology. (New)

→Glucocorticoids inhibit lipopolysaccharide-mediated inflammatory response by
downregulating microRNA-155: a novel anti-inflammation mechanism., Yijie Zheng,et al., 2012,Free Radical Biology & Medicine.

→Suppression of Type I Collagen Expression by miR-29b via PI3K, Akt, and Sp1 Pathway in Human Tenon’s Fibroblasts.,Ning Li, et al.,2012, Glaucoma. (New)

→Dysregulated expression of miR-146a contributes to agerelated dysfunction of macrophages.,Minghong Jiang, et al.,2011, Anatomical Society of Great Britain and Ireland.

→Overexpression of miR-125b, a novel regulator of innate immunity, in eosinophilic chronic rhinosinusitis with nasal polyps.,H X Zhang, et al., 2011, American Thoracic Society.Am. J. Respir. Crit.

→  MicroRNA-135a contributes to the development of portal vein tumor thrombus by promoting metastasis in hepatocellular carcinoma.Shupeng Liu, et al.,2011., Journal of Hepatology.

→  Signature microRNA Expression Profile of Essential Hypertension and Its Novel Link to Human Cytomegalovirus Infection. Li S., et al., 2011, Circulation.

→  Deregulated miR-155 promotes Fas-mediated apoptosis in human intervertebral disc degeneration by targeting FADD and caspase-3. Wang, H.Q., et al., 2011, J Pathol.

→  MicroRNA 345, a methylation-sensitive microRNA is involved in cell proliferation and invasion in human colorectal cancer. Tang J.T., Wang J.L., Du W., et al., 2011, Carcinogenesis.

→  Modulation of T cell cytokine production by miR-144* with elevated expression in patients with pulmonary tuberculosis. Yanhua Liu et al., 2011, Molecular Immunology.

→  A microRNA profile comparison between thoracic aortic dissection and normal thoracic aorta indicates the potential role of microRNAs in contributing to thoracic aortic dissection pathogenesis Mingfang Liao, et al. 2011, JOURNAL OF VASCULAR SURGERY.


→  MicroRNA Expression Analysis: Clinical Advantage of Propranolol Reveals Key MicroRNAs in Myocardial Infarction. Wenliang Zhu et al. 2011, PLoS ONE.

→  MiRNA profile in esophageal squamous cell carcinoma: Downregulation of miR-143 and miR-145. Wu, B.L., et al., 2011, World J Gastroenterol.

→  Comparison of microRNA profiles of human periodontal diseased and healthy gingival tissues. Xie, Y., et al., 2011, Int J Oral Sci.

→  TLR9 agonist enhances lung cancer invasiveness by alternating miRNA expression profile. Ren, T., et al., 2011, Scientific Research and Essays.

→  Identification of microRNA-target interaction in APRIL-knockdown colorectal cancer cells, F Wang, W Ding, J Wang, R Jing, X Wang, H Cong, Y Wang, S Ju and H Wang, Cancer Gene Therapy (2011) 18, 500-509.

→  MicroRNA-224 Is Involved in Transforming Growth Factor-β-Mediated Mouse Granulosa Cell Proliferation and Granulosa Cell Function by Targeting Smad4. Yao G.D., Yin M.M., Lian 2010, J., Mol. Endocrinol.

→  MiR-218 Inhibits Invasion and Metastasis of Gastric Cancer by Targeting the Robo1 Receptor.  Jun Tie, et al., 2010, Plos Genetics.

→  A Novel Function of MicroRNA Let-7d in Regulation of Galectin-3 Expression in Attention Deficit Hyperactivity Disorder Rat Brain. Wu , et al., 2010, Brain Pathol.

→  miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27Kip1-and MEK/ERK-mediated cell cycle regulation.  R., et al., 2010, Biological Chemistry.

→  Up-regulation of microRNA in bladder tumor tissue is not common. Gang Wang, et al., 2010, Int Urol Nephrol.

→  MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression. Ming Zhou, et al., 2010, J Biol Chem.

→  Regulation of NADPH Oxidase Activity Is Associated with miRNA-25-Mediated NOX4 Expression in Experimental Diabetic Nephropathy. Fu, Y., et al., 2010, American Journal of Nephrology.

→  Differential expression of microRNAs in porcine placentas on Days 30 and 90 of gestation. Su, L., et al., 2010, Reproduction, Fertility and Development.

→  MicroRNA profiling in mid- and late-gestational fetal skin: implication for scarless wound healing. Cheng J, et al., 2010, Tohoku J Exp Med.

→  MicroRNA145 Targets BNIP3 and Suppresses Prostate Cancer Progression. Xueqin Chen, et al., 2010, Cancer Res.

→  Altered microRNA expression in patients with non-obstructive azoospermia. Jie Liang, et al., 2009, Reprod. Biol. Endocrinol.

→  Regulation of Hepatic MicroRNA Expression in Response to Ischemic Preconditioning following Ischemia=Reperfusion Injury in Mice. Cheng-fu Xu, et al., 2009, OMICS A Journal of Integrative Biology.

→  MicroRNA: Novel Regulators Involved in the Remodeling and Reverse Remodeling of the Heart. Jue Wang, et al., 2009, Cardiology.

→  Repression of the miR-17-92 cluster by p53 has an important function in hypoxia-induced apoptosis.  Hong-li Yan, et al., 2009, EMBO J.

→  miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosis. Can-jie Guo, et al., 2009, J Hepatol.

→  Changes in microRNAs associated with hepatic stellate cell activation status identify signaling pathways.  Can-jie Guo, et al., 2009, FEBS J.

→  Embryonic stem cells derived from somatic cloned and fertilized blastocysts are post-transcriptionally indistinguishable: A MicroRNA and protein profile comparison.  Dingding Jun, et al., 2009, Proteomics.

→  Altered gene expression and miRNA expression associated with cancerous IEC-6 cell transformed by MNNG.  Bo Zhang, et al., 2009, J Exp Clin Canc Res.


→  Differential expression of miRNA patterns in renal cell carcinoma and nontumorous tissues.  Zhengjun Yi, et al., 2009, J CANCER RES CLIN.

→  Changes in microRNA profile and effects of miR-320 in insulin-resistant 3T3-L1 adipocytes. Ling HY, et al., 2009, CLIN EXP PHARMACOL P.

→  MicroRNA expression and regulation in mouse uterus during embryo implantation. Shi-Jun Hu, et al., 2008, J Biol Chem.

→  Microarray analysis of microRNA expression in hepatocellular carcinoma and non-tumorous tissues without viral hepatitis. Huang YS, et al., 2008, J Gastroen Hepatol.

→  Identification of Differentially Expressed MicroRNAs During the Development of Chinese Murine Mammary Gland. Chunmei Wang, et al., 2007, Journal of Genetics and Genomics.

→  The muscle-specific microRNA miR-1 regulates cardiac arrhythmogenic potential by targeting GJA1 and KCNJ2. Baofeng Yang, et al., 2007, Nature Medicine.

B. Publications by Exiqon microRNA PCR Array Service

→ Metformin alters the expression profiles of microRNAs in human pancreatic cancer cells., Weiguang Li, ect.January 2012., diabetes research and clinical practice. (New)

C. Publications by Arraystar LncRNA Microarray Service

→  Yang, F., Zhang L, et al., Long non-coding RNA high expressed in hepatocellular carcinoma (lncRNA-HEIH) facilitates tumor growth through enhancer of zeste homolog 2. Hepatology, 2011. (New)

D. Publications by SABiosciences Real-time PCR Array Service

→  Zhu W., et al.,Overexpression of EIF5A2 promotes colorectal carcinoma cell aggressiveness by upregulating MTA1 through C-myc to induce ithelialemesenchymal transition. (New)

→  Tong Ding, Limin Zheng, Endothelium-Coated Tumor Clusters Are Associated With Poor Prognosis and Micrometastasis of Hepatocellular Carcinoma After Resection. Cancer. 2011 Nov 1;117 (21): 4878-89.

→  Dong-Ming Kuang, Limin Zheng, Peritumoral neutrophils link inflammatory response to disease progression by fostering angiogenesis in hepatocellular carcinoma. Journal of Hepatology. 2011 vol. 54,  948–955.

→  Li Y., et al., ShRNA-Targeted Centromere Protein A Inhibits Hepatocellular Carcinoma Growth. Plos One, 2011. 6(3):e17794.

→  Zhang, L., et al., Escin attenuates cognitive deficits and hippocampal injury after transient global cerebral ischemia in mice via regulating certain inflammatory genes. Neurochem Int, 2010. 57(2): p. 119-27.

→  Xu, X.L., et al., The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor. Carcinogenesis, 2010. 31(2): p. 167-74.

→  Xu, Z.Y., J.S. Chen, and Y.Q. Shu, Gene expression profile towards the prediction of patient survival of gastric cancer. Biomed Pharmacother, 2010. 64(2): p. 133-9.

→  Duan, H., et al., Effect of burn injury on apoptosis and expression of apoptosis-related genes/proteins in skeletal muscles of rats. Apoptosis, 2009. 14(1): p. 52-65.

→  Gu, H., et al., Effects of chronic mild stress on the development of atherosclerosis and expression of toll-like receptor 4 signaling pathway in adolescent apolipoprotein E knockout mice. J Biomed Biotechnol, 2009. 2009: p. 613879.

→  Shi, W.D., et al., Identification of liver metastasis-related genes in a novel human pancreatic carcinoma cell model by microarray analysis. Cancer Lett, 2009. 283(1): p. 84-91.

E. Publications by Raybiotech Antibody Microarray Service
→  Yin, M., et al., Lack of apoE causes alteration of cytokines expression in young mice liver. Mol Biol Rep, 2010. 37(4): p. 2049-54.

→  Jiang, X., et al., Increased inflammatory response both in brain and in periphery in presenilin 1 and presenilin 2 conditional double knock-out mice. J Alzheimers Dis, 2009. 18(3): p. 515-23.

→  Li, H., et al., Dendritic cell-activated cytokine-induced killer cells enhance the anti-tumor effect of chemotherapy on non-small cell lung cancer in patients after surgery. Cytotherapy, 2009. 11(8): p. 1076-83.

→  Chen, L.L., et al., Evaluation of immune inhibitory cytokine profiles in epithelial ovarian carcinoma. J Obstet Gynaecol Res, 2009. 35(2): p. 212-8.

→  Niu, Q.X., et al., Induction of inflammatory cytokine release from human umbilical vein endothelial cells by agonists of proteinase-activated receptor-2. Clin Exp Pharmacol Physiol, 2008. 35(1): p. 89-96.

→  Qin, D., et al., Induction of lytic cycle replication of Kaposi's sarcoma-associated herpesvirus by herpes simplex virus type 1: involvement of IL-10 and IL-4. Cell Microbiol, 2008. 10(3): p. 713-28.

→  Li, A., et al., Dysfunction of splenic macrophages in cirrhotic patients with hypersplenism and HBV infection. Am J Med Sci, 2008. 336(1): p. 32-8.

→  Kong, X.N., et al., LPS-induced down-regulation of signal regulatory protein alpha contributes to innate immune activation in macrophages. J Exp Med, 2007. 204(11): p. 2719-31.

F. Publications by Springbio Antibody Microarray Service

→  Lou, J., et al., Comparison between two kinds of cigarette smoke condensates (CSCs) of the cytogenotoxicity and protein expression in a human B-cell lymphoblastoid cell line using CCK-8 assay, comet assay and protein microarray. Mutat Res, 2010. 697(1-2): p. 55-9.

→  Hao, Y., et al., IPO-38 is identified as a novel serum biomarker of gastric cancer based on clinical proteomics technology. J Proteome Res, 2008. 7(9): p. 3668-77.

G. Publications by Agilent Gene Expression Microarray Service

→ Zhang RK., et al., Gene Expression Analyses of Subchondral Bone in Early Experimental Osteoarthritis by Microarray .plos one, 2012. (New)

→Zhang RK., et al., Gene Expression Analyses of Subchondral Bone in Early Experimental Osteoarthritis by Microarray .plos one, 2012. (New)
→Ye, C., et al., Diabetes causes multiple genetic alterations and downregulates expression of DNA repair genes in the prostate. Laboratory Investigation, 2011. 91(9): p. 1363-1374.

→  Cheng, Y.M., M.L. Liu, and M.C. Jia, LM23 is a novel member of the Speedy/Ringo family at the crossroads of life and death of spermatogenic cell. Asian Journal of Andrology, 2011. 13(3): p. 446-452.

→  Ye, H., et al., Global transcriptional profiles of Mycobacterium tuberculosis treated with plumbagin. World Journal of Microbiology and Biotechnology, 2011: p. 1-9.

→  Liang, J., et al., Microarray Analysis of the Chelerythrine-Induced Transcriptome of Mycobacterium tuberculosis. Current microbiology, 2011: p. 1-9. 
→  Li, Y., et al., Gene expression profiling: identification of genes with altered expression in Ayu17-449 knockout mice. Genetics and Molecular Research, 2011. 10(3): p. 1533-1544. 
→  Ji-Lin Wang1., et al.,Calcium Prevents Tumorigenesis in a Mouse Model of Colorectal cancer. PLOS ONE., 2011. 
→  Wen Q., et al., Gene expression signature of lymphocyte in acute lymphoblastic leukemia patients immediately after total body irradiation. LEUK RES., 2011.

→  Cai J., et al., Apigenin inhibits hepatoma cell growth through alteration of gene expression patterns. Phytomedicine, 2011. 18(5):366-73.
→  Su J., et al., The existence of multipotent stem cells with epithelial–mesenchymal transition features in the human liver bud. Int J Biochem Cell Biol., 2010. 42(12):2047-55. 
→  Guo, X., et al., Homeobox gene IRX1 is a tumor suppressor gene in gastric carcinoma. Oncogene, 2010. 29(27): p. 3908-20.

H. Publications by ChIP/MeDIP Service

→  Liu, Z., et al., Potential Tumor Suppressor NESG1 as an Unfavorable Prognosis Factor in Nasopharyngeal Carcinoma. PLoS One, 2011. 6(11): p. e27887.
→  Zuping Zhang, Guiyuan Li1, et al., MiR-185 Targets the DNA Methyltransferases 1 and Regulates Global DNA Methylation in human glioma, Molecular Cancer 2011, 10:124.
→  Yi Zhang, Fu-qiang Chen, et al., Effects of DNMT1 silencing on malignant phenotype and methylated gene expression in cervical cancer cells. Journal of Experimental & Clinical Cancer Research 2011, 30:98.
→  Yan, X.J., et al., Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia. Nat Genet, 2011.
→  Li Lei, et al., Genome-wide DNA methylation patterns in IVF-conceived mice and their progeny: A putative model for ART-conceived humans. Reprod Toxicol, 2011.
→  Liu, B.L., et al., Quantitative detection of multiple gene promoter hypermethylation in tumor tissue, serum, and cerebrospinal fluid predicts prognosis of malignant gliomas. Neuro Oncol, 2010. 12(6): p. 540-8.
→  Zhang, L., et al., Genome-wide analysis of histone H3 lysine 4 trimethylation in peripheral blood mononuclear cells of minimal change nephrotic syndrome patients. Am J Nephrol, 2009. 30(6): p. 505-13.
→  Zhang, L., et al., Genome-wide analysis of histone H3 lysine 27 trimethylation by ChIP-chip in gastric cancer patients. J Gastroenterol, 2009. 44(4): p. 305-12.
→  Hu, J.L., et al., The N-terminus of histone H3 is required for de novo DNA methylation in chromatin. Proc Natl Acad Sci U S A, 2009. 106(52): p. 22187-92.

I. Publications by Agilent aCGH Service

→  Xu, X.L., et al., The properties of tumor-initiating cells from a hepatocellular carcinoma patient's primary and recurrent tumor. Carcinogenesis, 2010. 31(2): p. 167-74. primary amenorrhea and hyperandrogenism. Int J Gynaecol Obstet, 2010. 109(2): p. 164-6.

J. Publications by Roche-NimbleGen aCGH Service

→  Zhang, Y., et al., Array-CGH detection of UGT2B28 gene deletion in a girl with primary amenorrhea and hyperandrogenism. Int J Gynaecol Obstet, 2010. 109(2): p. 164-6.

K. Publications by Roche-NimbleGen Gene Expression Microarray Service

→  Liu, T., et al., Gene Expression Profiling of Rat Testis Development During the Early Post‐Natal Stages. Reproduction in Domestic Animals, 2011.(New)

→  Lu, Y., et al., Small interfering RNAs screened from random siRNA library direct neuronal differentiation. Biotechnology letters, 2011: p. 1-8. (New)

→  Liu, S., et al., MicroRNA-135a Contributes to the Development of Portal Vein Tumor Thrombus by Promoting Metastasis in Hepatocellular Carcinoma. Journal of Hepatology, 2011.

→  Zheng B, Han M, Shu YN, et al., HDAC2 phosphorylation-dependent Klf5 deacetylation and RARα acetylation induced by RAR agonist switch the transcription regulatory programs of p21 in VSMCs. Cell Res., 2011; doi:10.1038/cr.2011.34.

→  Fan, C., et al., Random small interfering RNA library screen identifies siRNAs that induce human erythroleukemia cell differentiation. Leuk Lymphoma, 2011. 52(3): p. 502-14.

→  Li, Z., et al., From the Cover: Feature Article: Histone H4 Lys 20 monomethylation by histone methylase SET8 mediates Wnt target gene activation. Proc Natl Acad Sci U S A, 2011. 108(8): p. 3116-23.

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